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Evolutionary Coupling Analysis

Predicted and experimental contacts

Interactive contact map

Secondary structure from ECs

Known pdb structures

pdb chain
2kpz A
2kq0 A
4n7h A

EC score distribution and threshold

Top ECs

Rank Residue 1 Amino acid 1 Residue 2 Amino acid 2 EC score
1 849 R 855 R 0.71
2 849 R 859 I 0.60
3 860 D 867 T 0.51
4 882 K 886 D 0.49
5 858 F 870 D 0.48
6 877 A 881 G 0.47
7 824 T 829 Q 0.46
8 826 D 831 V 0.45
9 879 L 883 T 0.45
10 881 G 886 D 0.44
11 883 T 887 T 0.42
12 822 A 826 D 0.41
13 823 S 829 Q 0.41
14 826 D 830 Q 0.40
15 847 E 861 H 0.39
16 881 G 885 L 0.39
17 877 A 882 K 0.39
18 822 A 827 S 0.39
19 845 G 862 N 0.39
20 848 V 857 F 0.38
21 831 V 835 S 0.38
22 848 V 853 N 0.37
23 880 R 885 L 0.37
24 848 V 858 F 0.37
25 850 H 856 P 0.37
26 861 H 866 T 0.36
27 851 A 857 F 0.36
28 822 A 829 Q 0.36
29 823 S 827 S 0.36

Alignment robustness analysis

First most common residue correlation

Second most common residue correlation

Robustness